社区单纯性肥胖症儿童血清Nesfatin-1含量变化情况观察

Observation of serum Nesfatin-1 level change condition of community simple obesity children

目的:观察单纯性肥胖症儿童血清Nesfatin-1含量的变化情况。方法:75例单纯性肥胖症儿童为观察组,75例正常儿童为对照组,对两组患者的空腹血清nesfatin-1水平进行检测,同时检查儿童BMI、血脂等,分析血清nesfatin-1与BMI之间相关性。结果:与对照组比较,观察组BMI指数高、LDL指数高、HDL指数低(P<0.05);对照组血清nesfatin-1与BMI无明显相关性,观察组血清nesfatin-1与BMI呈负相关。结论:对单纯性肥胖症儿童患者进行预测时可将血清Nesfatin-1含量作为评定疾病发生的指标。

Objective:To observe the serum Nesfatin-1 level change condition of community simple obesity children.Methods:75 cases of simple obesity children were as the observation group.75 cases of normal children were as control group.The fasting serum nesfatin-1 levels were detected between two groups,and the BMI and blood lipid of children were inspected.The correlation between serum nesfatin-1 and BMI was analyzed.Results:Compared with the control group,the BMI index of the observation group was high;the LDL index was high;the HDL index was low(P<0.05).The serum nesfatin-1 and BMI had no significant correlation in the control group.The serum nesfatin-1 and BMI was negatively correlated in the observation group.Conclusion:The serum Nesfatin-1 level can be used as an index to assess the occurrence of the disease in the prediction of simple obesity children.