厄贝沙坦氢氯噻嗪联合美托洛尔治疗老年慢性心力衰竭患者疗效观察

Curative effect observation of irbesartan hydrochlorothiazide combined with metoprolol in the treatment of elderly patients with chronic heart failure

目的:探讨厄贝沙坦氢氯噻嗪联合美托洛尔治疗老年慢性心力衰竭的临床疗效。方法:收治老年慢性心力衰竭患者50例,随机分为两组。对照组给予厄贝沙坦氢氯噻嗪治疗,观察组给予厄贝沙坦氢氯噻嗪联合美托洛尔治疗,对比两组总有效率及治疗前后BNP水平。结果:观察组总有效率高于对照组(P<0.05)。观察组治疗后BNP水平低于对照组(P<0.05)。结论:厄贝沙坦氢氯噻嗪联合美托洛尔治疗老年慢性心力衰竭可显著提高疗效,改善心功能。

Objective:To investigate the clinical curative effect of irbesartan hydrochlorothiazide combined with metoprolol in the treatment of elderly patients with chronic heart failure.Methods:50 cases of elderly patients with chronic heart failure were divided into two groups randomly.The control group was treated with irbesartan hydrochlorothiazide.The observation group was treated with irbesartan hydrochlorothiazide combined with metoprolol.The total effective rate and levels of BNP before and after the treatment in the two groups were compared.Results:The total effective rate of the observation group was higher than that of the control group (P<0.05).The levels of BNP in the observation group were lower than that in the control group (P<0.05).Conclusion:Irbesartan hydrochlorothiazide combined with metoprolol in the treatment of elderly patients with chronic heart failure could improve the curative effect significantly and the heart function.