乳腺分泌性癌的临床病理特征研究

Clinical pathological characteristics of secretory carcinoma of the breast

目的：对临床乳腺分泌性癌(SBC)患者的临床病理特征加以总结。方法：收治SBC 患者20 例，分析临床资料，对其临床病理特征加以总结。结果：20 例SBC 患者，女性95%，85%年龄≥30 岁，多在发病后1 个月来院就诊；经检查显示，80%患者肿瘤≥2 cm；病理类型方面，单纯SBC 占85%，少数伴有浸润性导管癌与导管内癌；60%患者淋巴结均为阴性，30%患者存在1～3 个阳性淋巴结；免疫组织检查提示，ER 阳性率35%，PR 与HER-2 的阳性率均为25%，S-100 阳性率95%。结论：明确SBC病症的病理特点对尽早确诊病症有着重要作用。

Objective:To sum up the clinical pathological characteristics of patients with secretory carcinoma of the breast(SBC).Methods:20 patients with SBC were selected,95% of women,85% aged 30 or above,after the onset of a month to the hospital,theexamination revealed,80% of cancer patients is more than or equal to 2 cm,pathological type,simple SBC accounted for 85% ,asmall number of patients with invasive ductal carcinoma and ductal carcinoma,60% lymph nodes were negative,30% patientswere 1 to 3 positive lymph nodes.The ER positive rate was 35%,PR and HER-2 positive rate was 25%,S-100 positive rate was95%.Conclusion:To clear the pathological characteristics of SBC disease,the early diagnosis of disease has an important role.