血清降钙素原预测脓毒血症患者预后的临床价值

Clinical value of serum procalcitonin in the prediction of the prognosis of patients with sepsis

目的:探讨血清降钙素原(PCT)监测在脓毒血症患者病情监测及预后中的临床价值。方法:收治56例脓毒血症患者作为观察组,同期收治55例非脓毒血症患者作为对照组,将观察组按预后情况再分为生存组与死亡组,每组28例,采用电化学发光法对患者PCT水平进行测定并比较分析。结果:随着病情的缓解,患者的血清PCT水平有明显降低;反之,血清PCT水平则有显著上升(P<0.05)。结论:脓毒血症患者的血清PCT水平有明显变化,对脓毒血症患者病情监测和预后评估有较大临床价值。

Objective:To explore the clinical value of serum procalcitonin(PCT) monitoring in the condition monitoring andprognosis of patients with sepsis.Methods:56 patients with sepsis were selected as the observation group.55 patients without sepsiswere selected as the control group.According to the prognosis,the observation group was divided into the survival group and thedeath group with 28 cases in each.The PCT levels of patients were determined by electrochemiluminescence and comparativelyanalyzed.Results:With the remission of the disease,the serum PCT levels of patients were significantly decreased,whereas theserum PCT levels were significantly increased(P<0.05).Conclusion:The serum PCT level of patients with sepsis has obviouschange,and it has a great clinical value on the condition monitoring and prognosis evaluation of patients with sepsis.