利福平注射液与利福平胶囊治疗初治空洞型肺结核的疗效研究

Curative effect research of rifampicin injection and rifampicin capsule in the treatment of primary cavitary pulmonary tuberculosis

目的:探讨利福平注射液与利福平胶囊治疗初治空洞型肺结核患者的疗效。方法:收治空洞型肺结核患者72例,随机分为两组。对照组给予利福平胶囊治疗,观察组给予利福平注射液治疗,比较两组疗效。结果:对照组总有效率79.2%,观察组总有效率94.4%,差异有统计学意义(P<0.05)。对照组不良反应发生率66.7%,观察组不良反应发生率22.2%,差异有统计学意义(P<0.05)。结论:利福平注射液治疗空洞型肺结核患者的疗效更显著,安全性更高。

Objective:To investigate the curative effect of rifampicin injection and rifampicin capsule in the treatment of patientswith primary cavitary pulmonary tuberculosis.Methods:72 cases of patients with cavitary pulmonary tuberculosis were divided intotwo groups randomly.The control group was treated with rifampicin capsule.The observation group were treated with rifampicininjection.The curative effect of the two groups was compared.Results:The total effective rate of the control group was 79.2%;thetotal effective rate of the observation group was 94.4% ;the difference was statistically significant(P<0.05).The incidence ofadverse effect in the control group was 66.7%;the incidence of adverse effect in the observation group was 22.2%;the differencewas statistically significant(P<0.05).Conclusion:Rifampicin injection in the treatment of cavitary pulmonary tuberculosis hadmore significant curative effect and higher safety.