黄体酮不同用药方式治疗先兆流产86例疗效分析

Curative effect analysis of progesterone different application methods in the treatment of threatened abortion in 86 cases

目的:探讨黄体酮不同用药方式治疗先兆流产的疗效。方法:将86例黄体功能不足引起早期先兆流产患者随机分为两组。试验组43例使用黄体酮针剂肌内注射,对照组43例口服黄体酮胶囊,比较两组临床疗效、血孕酮值的升高情况。结果:试验组保胎成功率95.3%,对照组保胎成功率97.7%,差异无统计学意义(P>0.05)。治疗后两组孕酮值均升高,试验组早于对照组。结论:黄体酮胶囊与肌内注射黄体酮治疗先兆流产均有较好的疗效。肌注在短期内提高血孕酮值,缓解临床症状;而口服黄体酮胶囊治疗后血孕酮值提高缓慢,但简单方便,缺点是药品价格稍偏贵,临床可根据患者病情及依从性使用。

Objective:To explore the curative effect of progesterone different application methods in the treatment of threatenedabortion.Methods:86 cases of corpus luteum insufficiency caused early threatened abortion patients were randomly divided intotwo groups.43 cases in the experimental group were given progesterone intramuscular injection.43 cases in the control group weregiven oral progesterone capsule.The clinical curative effects and serum progesterone values rising situation were comparedbetween groups.Results:The tocolytic success rate of the experimental group was 95.3%;the tocolytic success rate of the controlgroup was 97.7% ;the difference was not significant (P>0.05).Conclusion:Progesterone capsules and intramuscular injection ofprogesterone in the treatment of threatened abortion have good curative effects.Intramuscular injection in a short period canimprove the serum progesterone values,relieve the clinical symptoms.The serum progesterone values increase slowly after oralprogesterone capsule treatment,but it is simple and convenient,and the price is slightly expensive.In clinical it can be usedaccording to the patient's condition and compliance.