普洱市160株结核菌耐药性检测结果分析

Drug resistance results analysis of 160 strains of mycobacterium tuberculosis in Pu'er city

目的:探讨普洱市肺结核患者的耐药现状。方法:对肺结核病患者160例的痰培养物进行结核菌鉴定和耐药检测。结果:120株对抗结核药物I、R、S、E全部敏感(75%)。40株对1种或者1种以上的药物耐药(25%)。4种抗结核药物的耐药率分别为R 15.63%、E 13.75%、I 12.5%、S 12.5%。结论:普洱市目前结核病控制工作取得良好的效果,耐药性结核病,特别是耐多药结核病是防控工作的重中之重,需不断增强系统化管理和规范化治疗。

Objective:To investigate the drug resistance status of patients with pulmonary tuberculosis in Pu'er city.Methods:Themycobacterium tuberculosis were identified and drug resistance were detected in the sputum culture of 160 cases of patients withpulmonary tuberculosis.Results:120 strains were sensitive to anti-tuberculosis drugs of I,R,E and S (75% ).40 strains wereresistant to one or more than one kinds of drugs (25%).The drug resistance rates of the four kinds of anti-tuberculosis drugs wereR 15.63% ,E 13.75% ,I 12.5% ,S 12.5% .Conclusion:The tuberculosis control work in Pu'er city had good results,drug-resistanttuberculosis,especially multi drug-resistant tuberculosis was most important in the prevention and control work,which need tocontinue to enhance the system management and standardized treatment.