幽门螺杆菌与结肠腺瘤相关性的研究

Research on the correlation between helicobacter pylori and colonic adenoma

目的探讨幽门螺杆菌感染(Helicobacter pylori,H.pylori)和结肠腺瘤的关系。方法选取2014年1月至2015年5月就诊于我院有消化道症状或无症状体检患者,经结肠镜检查及病理证实为结肠腺瘤患者200例,无结肠腺瘤患者200例作为对照组,两组患者均行13C尿素呼气试验检查是否存在幽门螺杆菌感染,统计结果采用卡方检验,P<0.05时认为差异有统计学意义。结果 H.pylori感染合并结肠腺瘤的患者比例少于对照组,但两组数据比较差异无统计学意义。结论 H.pylori感染与结肠腺瘤的发生无明显相关性。

Objective To investigate the association between H.pylori infection and colon polyps.Methods Patients were selected in this study since January 2014 to May 2015. Two hundred patients werediagnosed colon polyps using colonoscopy and pathological biopsy, and 200 patients without colon polypsas the control group. All the patients underwent 13C-UBT tests, Chi-square tests were performed to determinestatistically significance between groups(P < 0.05). Results The percentage of H.pylori-positive patientswith colonic polyps was lower than those H.pylori-negative without colon polyps, the prevalence was notstatistically signifficant. Conclusion This study did not show the relevance between H.pylori infections andoccurrences of colonic polyps.