常规易测检验指标与慢性乙肝中医证型相关性

Correlation between routine test indexes and TCM syndrome types of chronic hepatitis B

目的:分析常规易测检验指标与慢性乙肝中医证型的相关性。方法:从我院2015年1月—2015年12月收诊的慢性乙肝患者中筛选出湿热中阻、肝郁脾虚、肝肾阴虚、脾肾阳虚、瘀血阻络型慢性乙肝患者各20例,选取正常体检者作为对照组。比较五组全血红细胞平均体积(MCV)、红细胞分布宽度(RDW)、血小板(PLT)、血小板平均体积(MPV)等指标。结果:1红细胞平均体积:湿热中阻组与瘀血阻络组与对照组相比有统计学意义(P<0.05)。2红细胞分布宽度:湿热中阻组、瘀血阻络组与对照组及肝郁脾虚组、肝肾阴虚组、脾肾阳虚组相比,差异有统计学意义(P<0.05)。3血小板:湿热中阻组、瘀血阻络组与对照组及肝肾阴虚组、脾肾阳虚组相比差异有统计学意义(P<0.05)。4血小板平均体积:湿热中阻组、瘀血阻络组与对照组及肝肾阴虚组、脾肾阳虚组相比差异有统计学意义(P<0.05)。结论:常规红细胞及血小板检测与慢性乙肝中医证型有一定的相关性,其中主要以湿热中阻型与瘀血阻络型最为显著,能作为中医证型的检测依据。

Objective: To analyze the correlation between routine test indexes and TCM syndrome types of chronic hepatitis B.Methods: Patients with chronic hepatitis B, treated in our hospital from January 2015 to December 2015, were identified as types of damp heat resistance, liver stagnation and spleen deficiency, yin deficiency of liver and kidney, yang deficiency of spleen and kidney, obstruction of collaterals by blood stasis, with 20 cases in each type. Normal physical examination patients were selected as the control group. The whole blood mean corpuscular volume (MCV), red cell distribution width (RDW), platelet (PLT), mean platelet volume (MPV) and other indicators of five groups were compared. Results: ① MCV: The difference between type of damp heat resistance, obstruction of collaterals by blood stasis and the control group was statistically significant (P<0.05). ② RDW: The difference between type of damp heat resistance, obstruction of collaterals by blood stasis and the control group and that of type of liver stagnation and spleen deficiency, yin deficiency of liver and kidney, yang deficiency of spleen and kidney was statistically significant (P<0.05). ③ PLT: The difference between type of damp heat resistance, obstruction of collaterals by blood stasis and the control group and that of type of yin deficiency of liver and kidney, yang deficiency of spleen and kidney was statistically significant (P<0.05). ④ MPV: The difference between type of damp heat resistance, obstruction of collaterals by blood stasis and the control group and that of type of yin deficiency of liver and kidney,yang deficiency of spleen and kidney was statistically significant (P<0.05). Conclusion: Conventional red blood cells and platelets test had certain correlation with TCM syndrome types of chronic hepatitis B, among which type of damp heat resistance and type of obstruction of collaterals by blood stasis were the most significant, which could be used as basses for the detection of TCM syndrome types.