乌灵胶囊治疗高血压病伴睡眠障碍对血压的影响

An effect of the Wuling capsule on blood pressure from hypertension plus sleep disorder

目的:观察乌灵胶囊治疗高血压伴睡眠障碍患者对其血压的影响。方法:入选高血压病合并中度睡眠障碍的患者,在常规降压等治疗的基础上加服乌灵胶囊,3次/d,3粒/次,治疗7d。观察乌灵胶囊治疗后患者的血压变化情况及不良反应。结果:乌灵胶囊治疗1周后,50例患者睡眠障碍明显改善,SRSS累计积分明显降低,前后对比P<0.01,差异有显著性意义;血压明显下降,收缩压下降(15.3±5.2)mm Hg,舒张压下降(7.6±3.1)mm Hg,前后对比P<0.01,差异有显著性意义。6例患者血压下降不明显,5例血压轻度升高,总有效率为80.36%,无其他明显不良反应。结论:采用乌灵胶囊治疗高血压病伴睡眠障碍患者,能改善失眠状态,有效降低血压。

Objective: To observe effects of the Wuling capsule on blood pressure from hypertension in patients with sleep disorder.Methods: Hypertension patients with sleep disorder were given the conventional antihypertension plus the Wuling capsule, 3 times daily, 3 capsulesper time, for 7 days. The change of blood pressure and adverse reactions were observed. Results: In 1 week, 50 patients with sleep disorders wereimproved; SRSS cumulative scores were decreased significantly, P<0.01. The blood pressure was decreased significantly; the systolic pressurewas decreased for (15.3±5.2) mmHg, and the diastolic blood pressure was dropped for (7.6±3.1) mmHg, P<0.01, with a significant difference.The blood pressure did not obviously change in 6 cases, and slight increase in 5 cases. The total efficiency was 80.36%, with no adverse reaction.Conclusion: Treating hypertension plus sleep disorder with the Wuling capsule can improve sleep state, and reduce the blood pressure.