在老年患者全麻诱导中应用舒芬太尼对血流动力学影响分析

Effect analysis of sufentanil on hemodynamics in elderly patients during general anesthesia induction

目的:探讨舒芬太尼在老年患者全麻诱导中对血流动力学的影响。方法:收治全麻手术老年患者50例,随机分为两组,每组25例。观察组给予舒芬太尼,对照组给予芬太尼,比较两组各个时间点心率、平均动脉压、心输出量、心脏指数。结果:观察组HR、MAP、CO、CI在T_1、T_2、T_3、T_4、T_5低于对照组,差异具有统计学意义(P<0.05)。观察组HR在T_4、T_5时间点高于T_1时间点,在T_3高于T_4、T_5时间点(P<0.05)。观察组MAP在T_3、T_4、T_5时间点显著高于T_2时间点(P<0.05)。观察组CO和CI在T_5时间点显著低于T_1时间点,在T_3时间点显著高于T_2时间点(P<0.05)。结论:舒芬太尼在老年患者全麻诱导中能更好地维持循环系统的稳定,对血流动力学无影响。

Objective:To investigate the effects of sufentanil on hemodynamics in elderly patients during general anesthesiainduction.Methods:50 cases of elderly patients with general anesthesia were divided into two groups randomly,with 25 cases ineach group.The observation group was given sufentanil,and the control group was given fentanyl.The heart rate,mean arterialpressure,cardiac output,cardiac index of the two groups at various points in time were compared.Results:The HR,MAP,CO,CI ofthe observation group at T1,T2,T3,T4,T5 time points were lower than those of the control group,and the differences were statisticallysignificant(P<0.05).The HR of the observation group at T4,T5 time points were higher than that at T1 time point,which at the T3time point was higher than that at T4,T5 time points (P<0.05).The MAP of the observation group at T3,T4,T5 time points were higherthan that at T2 time point (P<0.05).The CO,CI of the observation group at T5 time point were significantly higher than that at T1time point,which at the T3 time point was significantly higher than that at T2 time point (P<0.05).Conclusion:Sufentanil in elderlypatients during general anesthesia induction could maintain the stability of the circulatory system better and had no effect onhemodynamics.