老年轻度认知障碍患者Stroop效应的Logistic回归分析

Logistic regression analysis of Stroop effect in elderly patients with mild cognitive impairment

目的:探索老年轻度认知障碍患者的认知功能及Stroop效应临床应用的理论依据。方法:随机选取老年轻度认知障碍(MCI)患者46例,按1∶1匹配对照组,应用Stroop色字干扰测验评定两组的认知功能损害程度,采用Logistic回归分析Stroop效应指标与MCI的数量依存关系。结果:MCI组的Stroop效应耗时A卡、B卡、C卡、(C-B)/A和错误数A卡、B卡、C卡、(B-C)/A差异均有统计学意义(P<0.05或P<0.01);Stroop效应的logistic回归分析,耗时C卡、(C-B)/A和错误数B卡、C卡、(B-C)/A与MCI存在回归关系(P<0.05或P<0.01,均OR>1.0)。结论:MCI患者存在不同程度的认知功能损害,Stroop效应的测验工具应用起来客观、快速,有较好的筛检MCI的应用前景。

Objective:To explore the cognitive function of elderly patients with mild cognitive impairment and the theoreticalbasis for the clinical application of Stroop effect.Methods:46 patients with mild cognitive impairment(MCI)were randomly selected,and 1:1 matched control group.By Stroop Color word interference test evaluate cognitive impairment in the two groups.Logisticregression analysis was applied to evaluate the dependent relationship of Stroop effect index and the prevalence of MCI.Results:There were statistical significances between Stroop effect time-consuming of card A,card B,card C,(C-B)/A and error number ofcard A,card B,card C,(C-B)/A in the MCI case group(P<0.05 or P<0.01).Logistic regression analysis indicate that there wereregression relationship among time-consuming of card C,(C-B)/A and error number of card B,card C,(B-C)/A exist(P<0.05 orP<0.01).Conclusion:MCI patients have different degrees of cognitive impairment,and the Stroop effect test implement is objectiveand quick.It has a good prospect for the application of MCI diagnosis and screening.