精氨酸牙膏对成都农村儿童龋病预防效果的研究

Study on the anti-caries efficacy of arginine dentifrice on early childhood caries in Chengdu rural areas

目的研究精氨酸牙膏对成都农村儿童龋病的预防效果,以探索更好的龋病早期干预措施。方法随机抽取成都农村地区小学,按纳入和排除标准完成受试者筛选,将所有受试者随机分为2组,试验组使用含1.5%精氨酸及1 450 ppm F-的牙膏,对照组使用含1 450 ppm F-的牙膏,对2组受试者进行口腔龋病的全面检查并记录。检查结果均通过epidata软件进行数据录入,使用SPSS 13.0统计软件分析数据。结果1年后,试验组患龋率及龋均明显低于对照组。试验组乳牙新增龋失补牙数(t=1.58,P=0.001)、新增龋失补牙面数(t=1.16,P=0.001)低于对照组,恒牙新增龋失补牙数(t=1.02,P=0.005)、恒牙新增龋失补牙面数(t=1.03,P=0.002)均低于对照组,且差异具有统计学意义。结论含1.5%精氨酸及1 450 ppm F-的牙膏较含1 450 ppm F-的牙膏对儿童龋病预防效果更显著。

Objective To study the anti?caries efficacy of arginine dentifrice on early childhood caries in the ruralarea of Chengdu city in order to explore better early intervention measures on caries. Methods Two schools in Cheng?du rural area were randomly chosen. Subjects were chosen according to the inclusion and exclusion criteria. All sub?jects were randomly divided into 2 groups, the experimental group used toothpaste containing 1.5% arginine and 1 450F- ppm, control group used toothpaste containing 1 450 F- ppm, a comprehensive inspection of the dental caries of the 2groups of subjects were recorded. The results were recorded by EpiData software for data entry, using SPSS 13.0 statisti?cal software analysis data. Results 1 years later, the prevalence, the mean decayed missing filled teeth of deciduousteeth (dmft) of the experimental group was significantly lower than the control group. The number of new dmft score (t =1.58, P = 0.001), the new decayed missing filled teeth surfaces (dmfs) number (t = 1.16, P = 0.001), The new perma?nent teeth DMFT number (t = 1.02, P = 0.005), new permanent teeth decay missing filling surface number (t = 1.03,P = 0.002) in the experimental group of deciduous teeth were lower than the control group. And the difference was sta?tistically significant. Conclusion Toothpaste containing 1.5% arginine and 1 450 F- ppm is more significant on chil?dren??s dental caries prevention effect compared with the toothpaste containing 1 450 F- ppm only.