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PCI及替罗非班冠脉-静脉给药治疗急性ST段抬高型心肌梗死的临床观察 被引量:1

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摘要 目的评析急性ST段抬高型心肌梗死给予PCI治疗及替罗非班冠脉-静脉给药的临床效果。方法对照组47例急性ST段抬高型心肌梗死患者在PCI治疗基础上给予替罗非班静脉给药,治疗组47例患者同时还配合冠脉内替罗非班给药,完成治疗后比较两组患者ST段抬高回落情况的差异,统计两组术后再灌注指标、LVEF、终末出血事件。结果治疗组患者的术后ST段抬高回落良好率为95.7%,与对照组的74.5%相比,差异有统计学意义(P<0.05);治疗组患者的术后TIMI血流3级率、CTFC、CK-MB峰值及其时间、LVEF等与对照组相比均明显更优(P<0.05);两组血小板减少、颅内出血及穿刺点出血/血肿发生率与对照组相比,差异无统计学意义(P>0.05)。结论针对行PCI治疗的急性ST段抬高型心肌梗死患者给予替罗非班冠脉-静脉给药治疗ST段抬高回落效果理想,有助于改善冠脉血流与心肌灌注,并且不增加出血事件,安全可靠。
作者 王洪涛
出处 《中国处方药》 2016年第10期83-84,共2页 Journal of China Prescription Drug
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