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多发性硬化中miRNA对神经胶质细胞的影响

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摘要 微小RNA(microRNA,miRNA)作为一种重要的基因转录后水平的负性调节因子,调控主要的神经胶质细胞如少突胶质细胞、小胶质细胞和星形胶质细胞在多发性硬化(multiplesclerosis,MS)发病的作用。利用miRNA,尤其是神经胶质细胞中特异性表达的miRNA来研究MS的发病机制,必将为该病的药物研发和诊治提供新的思路。本文就miRNA对MS中神经胶质细胞的作用的相关研究进展进行简要综述。一。
出处 《脑与神经疾病杂志》 2016年第10期657-661,共5页 Journal of Brain and Nervous Diseases
基金 河北省自然科学基金(H2014206463)
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