左氧氟沙星胶囊治疗耐多药肺结核及不良反应临床分析

Clinical analysis of left ofloxacin capsules in the treatment of multi drug resistant pulmonary tuberculosis and adverse reactions

目的:分析左氧氟沙星胶囊治疗耐多药肺结核致不良反应的临床因素。方法:收治耐多药肺结核患者50例,按照治疗方式分为研究组与对照组各25例。研究组给予左氧氟沙星胶囊治疗,对照组给予氧氟沙星胶囊治疗,比较两组患者的病灶吸收状况及临床不良反应。结果:研究组的病灶吸收率显著高于对照组(P<0.05);研究组不良反应发生率明显低于对照组(P<0.05)。结论:左氧氟沙星胶囊治疗耐多药肺结核患者能够提高病灶对药物的吸收效率,减少临床不良反应。

Objective:To analyze the clinical factors of adverse reactions caused by left ofloxacin capsules in the treatment ofmulti drug resistant pulmonary tuberculosis.Methods:50 patients with multi drug resistant pulmonary tuberculosis were selected.According to the treatment methods,they were divided into the study group and the control group with 25 cases in each.The studygroup was given left ofloxacin capsules treatment.The control group was given ofloxacin capsules treatment.The lesions absorptionstatus and clinical adverse reactions of two groups were compared.Results:The lesions absorption rate of the study group wassignificantly higher than that of the control group(P<0.05).The incidence of adverse reactions in the study group was significantlylower than that of the control group(P<0.05).Conclusion:Left ofloxacin capsules in the treatment of multi drug resistantpulmonary tuberculosis can improve the absorption efficiency of the drug,reduce the clinical adverse reactions.