^(131)I治疗甲状腺功能亢进的效果评估及分析

Effect evaluation and analysis of ^(131)I in the treatment of hyperthyroidism

目的:研究^(131)I治疗甲状腺功能亢进的效果。方法:收治甲状腺功能亢进患者360例,随机分为传统组和^(131)I组。传统组给予抗甲状腺药物治疗;^(131)I组给予^(131)I治疗。比较两组患者的总有效率、治愈率、不良反应率、复发率,比较治疗前和治疗后患者三碘甲状腺原氨酸和四碘甲状腺原氨酸水平的差异。结果:^(131)I组患者的总有效率、治愈率高于传统组(P<0.05);^(131)I组患者的不良反应率、复发率低于传统组(P<0.05);治疗后,^(131)I组三碘甲状腺原氨酸和四碘甲状腺原氨酸水平改善情况明显优于传统组(P<0.05)。结论:^(131)I治疗甲状腺功能亢进的效果确切,可有效改善患者三碘甲状腺原氨酸和四碘甲状腺原氨酸水平,且不良反应少,安全性高,可降低复发率。

Objective:To study the effect of 131I in the treatment of hyperthyroidism.Methods:360 patients with hyperthyroidismwere selected.They were randomly divided into the traditional group and the 131I group.The traditional group was given anti thyroiddrug treatment.The 131I groups was given 131I treatment.The total efficiency,cure rate,adverse reaction rate and recurrence rate ofthe two groups were compared,and the differences of the levels of triiodothyronine and tetraiodothyronine were compared beforeand after treatment.Results:The total efficiency and the cure rate of the 131I group were higher than those of the traditionalgroup(P<0.05).The adverse reaction rate and recurrence rate of the 131I group were lower than those of the traditional group(P<0.05).After treatment,the triiodothyronine and tetraiodothyronine level improvements of the 131I group were better than those of thetraditional group(P<0.05).Conclusion:The 131I in the treatment of hyperthyroidism has an accurate effect,can effectively improvethe triiodothyronine and tetraiodothyronine levels,and the adverse reaction is low,the safety is high,it can reduce the recurrencerate.