胺碘酮治疗急性心肌梗死后室性心律失常临床研究

Clinical study of amiodarone in the treatment of ventricular arrhythmias after acute myocardial infarction

目的:探讨胺碘酮治疗急性心肌梗死后室性心律失常的疗效。方法:收治急性心肌梗死后室性心律失常患者82例,随机分为两组。对照组给予利多卡因治疗,观察组给予胺碘酮治疗,比较两组治疗有效率、平均复律时间以及不良反应发生率。结果:观察组治疗有效率明显高于对照组,差异有统计学意义(P<0.05)。观察组平均复律时间短于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:胺碘酮治疗急性心肌梗死后室性心律失常能有效地缩短复律时间,提高治疗有效率,降低了不良反应率的发生率。

Objective:To investigate the curative effect of amiodarone in the treatment of ventricular arrhythmias after acutemyocardial infarction.Methods:82 cases of patients with ventricular arrhythmias after acute myocardial infarction were dividedinto two groups randomly.The control group was given lidocaine treatment.The observation group was given amiodarone treatment.The treatment effective rate,average cardioerter time and incidence of adverse reactions in the two groups were compared.Results:The treatment effective rate of the observation group was significantly higher than that of the control group,and the difference wasstatistically significant (P<0.05).The average cardioerter time of the observation group was shorter than that of the control group,and the difference was statistically significant (P<0.05).The incidence of adverse reactions in the observation group wassignificantly lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion:Amiodaronein the treatment of ventricular arrhythmias after acute myocardial infarction could shorten the cardioerter time effectively,improvetreatment effective rate and reduce the incidence of adverse reaction.