大株红景天注射液对不稳定性心绞痛患者的疗效及血氧的影响

Effective observation on efficacy of the Dazhu Hongjingtian injection on unstable angina and blood oxygen

目的:观察大株红景天注射液对不稳定性心绞痛患者的临床疗效及对血氧的影响。方法:将80例符合纳入标准的不稳定性心绞痛患者随机分为两组,对照组40例给予抗血小板、调脂、抗凝、扩冠等治疗,红景天组40例在基础治疗上加用大株红景天注射液进行治疗,以14d为一个疗程。观察两组治疗后临床症状、心电图变化程度,以及治疗前后的血气分析指标。结果:1治疗后两组临床疗效差异显著,有统计学意义(P<0.05);2治疗后两组心电图变化程度的差异显著,有统计学意义(P<0.05);3血氧饱和度方面,红景天组治疗前后有差异,但无统计学意义(P>0.05);4血氧分压方面,红景天组治疗前后差异显著,有统计学意义(P<0.05);治疗后两组的血氧分压含量差异显著,有统计学意义(P<0.05)。结论:大株红景天注射液可改善不稳定性心绞痛患者机体缺氧、缺血状态,有效减少缺氧所致的心绞痛事件。

Objective: To observe clinical effects of the Dazhu Hongjingtian injection on unstable angina and blood oxygen.Methods: 80 patients with unstable angina were randomly divided into two groups; the control group of 40 patients was given antiplatelet,anticoagulant, lipid regulation, crown expansion and other treatment; the Hongjingtian group of 40 patients was given the Dazhu Hongjingtian injection more; two groups were treated for 2 weeks; then clinical symptoms, the electrocardiogram changes, arterial blood gas analysis in groups were observed. Results: Clinical symptoms in groups showed a significant difference, P<0.05; ECG changes were statistically significant difference between groups, P<0.05; the oxygen saturation in the Hongjingtian group showed differences, without a statistically significant difference between before and after treatment (P>0.05); partial pressure of blood oxygen in the Hongjingtian group showed a statistically significant difference between before and after treatment (P<0.05); and there was a statistically significant difference in the partial pressure of blood oxygen between two groups after treatment (P<0.05). Conclusion: The Dazhu Hongjingtian injection can improve hypoxia and ischemia in patients with unstable angina, and reduce angina events from hypoxia.