摘要
目的研究中文版蒙特利尔认知评估量表(Mo CA)和简易精神状态量表(MMSE)在判定帕金森病患者认知障碍中的作用。方法帕金森病认知功能损害患者(PD-MCI)27例,年龄教育程度匹配的对照组31例,分别进行简易精神状态量表(MMSE)、Mo CA量表检测,分析比较两量表的敏感性、特异性和各量表的子项得分。结果根据两组的教育背景,以26分为界值,Mo CA、MMSE对PD-MCI诊断的敏感性分别为:70.37%、14.81%;特异性分别为:83.87%和93.55%。Mo CA对PD-MCI的敏感性高于MMSE。PD-MCI组在MMSE测试中,仅有两个子项目(计算力及注意力、延迟回忆)得分明显低于对照组,而在Mo CA测试中PD-MCI组在视空间与执行功能、延迟回忆、语言功能、抽象能力方面得分明显低于对照组。结论 MMSE不适于PD-MCI患者的筛查。Mo CA在对PD认知功能判定方面优于MMSE,尤其是执行功能及视空间方面。
Objective To study the effect of the Chinese version of Montreal Cognitive Assessment ( MoCA) and Mini - Mental State Examination (MMSE) in Parkinsons disease (PD) patients. Methods Twenty - seven PD pa-tients with mild cognitive impairment( PD-MCI) and 31 normal control subjects were evaluated by MMSE and MoCA. The sensitivity and specificity of two scales were compared and analyzed. Results According to the educational back-ground of two groups,the sensitivity of MoCA and MMSE on PD - Cl were 70. 37% and 14. 81% respectively by 26 as the cut - off point, the specificity were 83. 87% and 93. 55% respectively. The sensitivity of MoCA was higher than MMSE in diagnosing PD - MCI. The scores of calculation and attention of PD-MCI group were lower than control group in MMSE test; and visuospatial,executive function,delayed recall,language function,abstract ability scores of PD-MCI were significantly lower than the control group in MoCA test. Conclusion MMSE is not suitable for screening patients with PD-MCI. MoCA is better than MMSE in the cognitive function judgment of PD, particularly for visuospatial and ex-ecutive function.
作者
董艳娟
蔡晓平
李国英
李慧莉
Dong Yanjuan;Cai Xiaoping;Li Guoying;Li Huili(Department of Geriatirc Neurology ^General Hospital of Beijing Command Area ,PLA, Beijing100700,China)
出处
《中国临床保健杂志》
CAS
2016年第2期144-146,共3页
Chinese Journal of Clinical Healthcare
关键词
帕金森病
认知障碍
精神病状态评定量表
arkinson disease
C ognition d iso rd e rs
P sychiatric status ra tin g scales