超声介入下聚桂醇注射联合清宫术与甲氨碟呤肌内注射联合清宫术治疗剖宫产瘢痕妊娠的疗效对比观察

Comparative study of curative effect of interventional ultrasound poly cinnamyl alcohol injection combined with curettage surgery and intramuscular injection of MTX combined with curettage surgery in the treatment of cesarean section to produce scar pregna

目的:对比超声介入下聚桂醇注射联合清宫术和甲氨碟呤(MTX)肌内注射联合清宫术治疗剖宫产瘢痕妊娠患者的临床疗效。方法:将收治的60例剖宫产瘢痕妊娠患者随机分为聚桂醇组和MTX组,予以聚桂醇组患者超声介入下聚桂醇注射联合清宫术治疗,予以MTX组患者MTX肌内注射联合清宫术治疗。结果:聚桂醇组治疗过程中的阴道出血量少于MTX组(P<0.05),治疗过程中及清宫术后HCG的下降速度均快于MTX组(P<0.05),中转手术比例低于MTX组(P<0.05),术后1个月、3个月两组瘢痕处宫壁厚度比较差异无统计学意义(P>0.05),聚桂醇组瘢痕处血流RI值较MTX组高(P<0.05)。结论:超声介入下聚桂醇注射联合清宫术治疗剖宫产瘢痕妊娠患者,创伤小,安全性好,疗效确切。

Objective To compare curative effect of interventional ultrasound poly cinnamyl alcohol injection combined with curettagesurgery and intramuscular injection of MTX combined with curettage surgery in the treatment of cesarean section to producescar pregnancy. Method 60 case of patients with cesarean section scar pregnancy were randomly divided into lauromacrogol groupand MTX group, the lauromacrogol group received ultrasound intervention under lauromacrogol injection combined with curettagetreatment, the MTX group received injected MTX combined curettage treatment. Results The amount of vaginal bleeding was lessthan that of MTX group in the treatment of polyol group (P <0. 05) ,In the course of treatment and after curettage of HCG reductionrate was faster than that of MTX group(P <0. 05) ,the proportion of transit surgery was less than that of MTX group (P <0. 05) ,afterone month, three months both groups showed no scar palace wall thickness significantly different ( P > 0. 05 ) , The RI value ofblood flow in the scar of the alcohol group was higher than that in the MTX group ( P <0. 05). Conclusion Percutaneous injectionunder lauromacrogol curettage treatment combined with patient cesarean scar pregnancy, trauma, safety, and effective.