期刊文献+

胆红素与冠心病的发病关系 被引量:2

下载PDF
导出
摘要 目的:分析胆红素与冠心病的发病关系。方法:选取冠心病患者76例,设为观察组;另选择体检的76例健康人士,设为对照组;对152例均采取清晨空腹抽取静脉血,并进行血液检测,对比两组间总胆红素(TBil)、直接胆红素(DBi L)以及间接胆红素(IBi L)的浓度。结果:观察组的直接胆红素浓度(2.26±1.90)μmol/L、间接胆红素浓度(7.36±2.12)μmol/L、总胆红素浓度(10.01±3.85)μmol/L,均低于对照组的(3.97±1.81)μmol/L、(9.65±2.50)μmol/L、(12.53±3.62)μmol/L。结论:胆红素具有抗氧化、抗炎性、抗自由基,提升血红素氧化酶活性以及降脂的作用。能够降低血液的胆固醇,避免冠状动脉粥样硬化,有效地降低了冠心病的发病几率。
作者 郝东亚
出处 《吉林医学》 CAS 2016年第7期1770-1771,共2页 Jilin Medical Journal
  • 相关文献

参考文献6

二级参考文献59

  • 1陈正贵,顾向明,马立坚,缪灿铭.低血清胆红素与冠心病关系的研究[J].中国医药,2006,1(2):67-68. 被引量:3
  • 2翟锬,江东红,李华,刘彦慧.冠心病患者血清总胆红素水平的临床研究[J].中国心血管杂志,2006,11(4):266-268. 被引量:3
  • 3Schwertner HA, Jackson WG, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery dis- ease[J]. Clin Chem, 1994, 40(1):18-23.
  • 4Hopkins PN,Wu LL,Hunt SC,et al.Higher serum bilirubin is associ- ated with decreased risk for early familial coronary artery disease [J].Arterioscler Thromb Vasc Biol, 1996,16(2):250-255.
  • 5Brand FN, Megee DL, Kannel, WB, et al. Hyperuricenmia as a risk of coronary heart disease: the framingham study. Am J Epidemiol,1985,121:11-18.
  • 6Freedam DS, Williamson DF, Gunter EW, et al. Relation of serum uric acid to mortality and ischemic heart disease. The nhanesi epidemiologic follow up study. Am J Epidemiol, 1995,141:637-644.
  • 7Puddu PE, Lanti M, Menotti A, et al. Sermn uric acid for short-term prediction of cardiovascular disease incidence in the Gubbio population Study. Acta Cardiol, 2001,56:243-251.
  • 8Wang CY,Chau LY. Heme oxygenase 1 in cardiovascular dis- eases:Molecular mechanisms and clinical perspectives. Chang Gung Medical Journal,2010,33 : 13 24.
  • 9Dulak J, Deshane J, Jozkowicz A, et al. Heme oxygenase-1 and carbon monoxide in vascular pathobiology: Focus on angio- genesis. Circulation, 2008,117 : 231-241.
  • 10Wu ML, Ho YC, Yet SF. A central role of heine oxygenase-1 in cardiovascular protection. Antioxid Redox Signal, 2011,15: 1835-1846.

共引文献123

同被引文献16

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部