应用参芎葡萄糖注射液预防腰椎骨折后路手术术后静脉血栓形成的临床研究

Clinical study of using Shenxiong glucose injection in the prevention of venous thrombosis after lumbar fracture posterior surgery

目的:观察参芎葡萄糖注射液预防腰椎骨折行后路手术术后深静脉血栓形成的临床效果。方法:收治腰椎骨折并行后路手术患者120例,随机分成观察组与对照组。对比两组治疗前后的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、D-二聚体(D-D)、切口的引流量等指标变化,以及下肢静脉血栓的发生率。结果:观察组的静脉血栓发生率远低于对照组,观察组D-D含量较对照组明显下降。结论:采用参芎葡萄糖注射液可减少下肢深静脉血栓发生率,优化防治效果,并能够改善其血液流变学指标。

Objective:To observe the clinical effect of Shenxiong glucose injection in the prevention of deep venous thrombosisafter lumbar fracture posterior surgery.Methods:120 patients with lumbar fracture posterior surgery were selected.They wererandomly divided into the observation group and the control group.The prothrombin time(PT),activated partial thrombintime(APTT),D-two polymer(D-D),incision drainage and other indicators changes,and the incidence rate of lower limb venousthrombosis of two groups were compared before and after treatment.Results:The incidence rate of venous thrombosis inobservation group was much lower than that of the control group,and the D-D content of the observation group was significantlylower than that of the control group.Conclusion:Using Shenxiong glucose injection can reduce the incidence rate of lower limbdeep venous thrombosis,optimize the prevention and treatment effect,and it can improve the blood rheology indexes.