异常凝血酶蛋白在HBV相关肝癌中的诊断价值研究

Diagnostic value research of prothrombin precursor protein in HBV related hepatic carcinoma

目的:探究异常凝血酶蛋白在HBV相关肝癌中的诊断价值。方法:收治原发性肝癌患者120例,其中HBV相关肝癌60例作为观察组,非HBV相关肝癌60例作为对照组。比较两组PIVKA-Ⅱ、AFP水平。结果:观察组PIVKA-Ⅱ、AFP水平明显高于对照组(P<0.05)。PIVKA-Ⅱ诊断HBV相关肝癌的准确率高于AFP(P<0.05)。结论:HBV相关肝癌患者PIVKA-Ⅱ和AFP水平均较高,且PIVKA-Ⅱ诊断的准确率更高。

Objective:To explore the diagnostic value of prothrombin precursor protein in HBV related hepatic carcinoma.Methods:Among 120 cases of patients with primary hepatic carcinoma,60 cases of HBV related hepatic carcinoma were as theobservation group,and 60 cases of non-HBV related hepatic carcinoma were as the control group.The levels of PIVKA-Ⅱ,AFPbetween the two groups were compared.Results:The levels of PIVKA- Ⅱ and AFP in the observation group were significantlyhigher than those in the control group (P<0.05).The accuracy rate of PIVKA- Ⅱ in the diagnosis of HBV related hepaticcarcinoma was higher than that of AFP (P<0.05).Conclusion:The levels of PIVKA-Ⅱ and AFP in patients with HBV relatedhepatic carcinoma were higher,and the diagnostic accuracy of PIVKA-Ⅱ was higher.