比拜克胶囊治疗轻中度寻常性痤疮30例疗效观察

Clinical observation of Bibaike Capsules Effect on mild to medium degree acne vulgaris

目的:观察比拜克胶囊治疗轻、中度寻常性痤疮的疗效及安全性。方法:选取笔者科室就诊的60例轻中度寻常性痤疮患者,随机分为治疗组及对照组,每组各30例。两组患者均外用克林霉素磷酸酯凝胶,治疗组患者每日口服比拜克胶囊,对照组患者每日口服丹参酮胶囊。用药8周后观察两组疗效指标评分和不良反应发生率。结果:治疗组和对照组的总有效率分别为76.7%和70.0%,两组比较差异无统计学意义(P>0.05);治疗期间均未发生明显不良反应。结论:比拜克胶囊治疗轻、中度寻常性痤疮具有较好的临床疗效,值得临床推广应用。

Objective In this study, we observed the clinical effect and safety of Bibaike Capsules on mild to medium degree acne vulgaris. Methods 60 cases of patients clinically diagnosed with mild medium degree acne vulgaris were randomly and averagely divided into two groups, the therapy group and the control group. Both of the two groups used clindamycin gel externally.The therapy group was treated with bibaike capsules, and the control group used tanshinone capsules.After 8 weeks,we observed and analyzed the curative effect score and the incidence of adverse reaction. Results The total effective rate of therapy group was 76.7%, while 70.0% in control group. And the difference wasn’t statistically significant (P >0.05). There were no obviously adverse reactions observed in two groups. Conclusion Bibaike Capsules is effective for the treatment of mild to medium degree acne vulgaris.