奥拉西坦治疗脑梗死恢复期患者轻度认知功能障碍的临床效果分析

Analysis of the clinical effect of oxiracetam in treatment of mild cognitive impairment in patients with cerebral infarction at convalescence

目的:探讨奥拉西坦治疗脑梗死恢复期患者轻度认知障碍的临床效果。方法:收治脑梗死恢复期患者56例,平分为两组,观察组给予奥拉西坦注射液治疗,对照组采用依达拉奉注射液治疗,对比两组治疗后的治疗效果Mo CA评分及两组的并发症情况。结果:观察组患者的Mo CA评分(27.3±1.8)分,明显高于对照组的(26.9±2.3)分,组间差异具有统计学意义(P<0.05);两组患者治疗之后均没有出现明显的不良反应,有轻微失眠症状自行消失。结论:对脑梗死恢复期患者应用奥拉西坦治疗可以明显改善患者的认知障碍。

Objective:To investigate the clinical effect of oxiracetam in treatment of mild cognitive impairment in patients withcerebral infarction at convalescence.Methods:56 patients with cerebral infarction at convalescence were selected.They wererandomly divided into the two groups on average.The observation group was received the treatment of oxiracetam injection.Thecontrol group was treated by edaravone injection.We compared the therapeutic effect by MoCA scores after treatment and thecomplications of the two groups.Results:The MoCA score(27.3±1.8)in the observation group was significantly higher than that inthe control group of(26.9±2.3),and the difference between groups was statistically significant(P<0.05).There were no obviousadverse reactions in the two groups after treatment,and the symptoms of mild insomnia disappeared.Conclusion:Oxiracetam in thetreatment of patients with cerebral infarction in the recovery stage can significantly improve patients with cognitive impairment.