微波消解-ICP-MS测定中成药胶囊中15种金属元素

Determination of 15 Metals in Traditional Chinese Medicine and Capsules by Microwave Digestion and ICP-MS

采用硝酸-过氧化氢体系微波消解,以钪、铟作内标,电感耦合等离子体质谱法(ICP-MS)同时测定几种中成药及空心胶囊中的15种金属元素,各元素方法检出限在0.0007~0.047μg/g之间,相对标准偏差小于10%,标准物质加标回收率在82.3%~116%之间.方法简便快捷,灵敏度高,重现性好,是测定中成药及其空心胶囊中多元素高效、准确的方法.

15 metals in traditional Chinese medicine and capsules were determined simultaneously by microwave digestion and inductively coupled plasma mass spectrometry(ICP-MS). Scandium and Indium were used as the internal standards.The results showed that the detection limits of the 15 metals were between 0. 000 7 ~ 0. 047 μg/ g and all the relative standard deviations were less than 10%. The spiked recovery rates were between 82. 3% ~ 116%. The method can be effectively applied to the determination of aquatic products because of rapidness, high sensitivity and good reproducibility.