精神因素对功能性胃肠病影响及中医药干预研究进展

Research Progress in the Effects of Psychological Factors in Functional Gastrointestinal Disease and TCM Intervention

功能性胃肠病是一组无器质性病变的临床综合征,其多种临床症状有一定特异性且有重叠现象,机制尚不明确。中医学认为精神因素是其重要病因,情志不遂可通过肝、心直接或间接影响脾胃功能。目前,精神因素与功能性胃肠病的关系逐渐受到关注,公认的精神因素可能相关机制有脑肠轴功能紊乱、肥大细胞活化、肠道菌群失调等。本文从上述机制分别进行阐述,并综述近年来中医药对功能性胃肠病的干预进展。

Functional gastrointestinal disease is a group of clinical syndrome of non-organic disease. Its various clinical symptoms have a certain specificity and overlap phenomenon, and the mechanism is not clear. TCM believes thatphychological factorsare an important cause. Emotion failurecan effect spleen and stomach functionthrough liver and heart directly or indirectly.At present, the phychological factors and the relationship between functional gastrointestinal disease are getting attentiongradually. It is recognized that the mechanism of phychological factorsmay be related to brain axis dysfunction, mast cell activation, intestinal flora and so on. This article expounded the above-mentioned mechanism and reviewed the detailed TCM intervention measures to functional gastrointestinal disease in recent years.