天津市和平区成年人内脏型肥胖与高尿酸血症的关系

The relationship between visceral obesity and hyperuricemia in adults of Heping District of Tianjin

目的分析内脏型肥胖与高尿酸血症（HUA）的关系，为进一步研究肥胖和HUA的关系提供依据。方法选取2014年在天津市和平区健康教育指导中心进行健康体检的1824例体检人员作为研究对象，对所有研究对象进行体格检查和生化指标检查，并测量内脏脂肪面积（VFA）。采用Logistic回归分析内脏型肥胖与HUA之间的关系。结果随着VFA的增大，男、女性HUA的患病率呈上升趋势（P＜0.05）；且VFA、腰围（WC）和腰臀比（WHR）与血尿酸（SUA）水平均呈正相关（P＜0.05）。Logistic多因素回归分析显示，男性VFA（OR=1.805，95%CI=1.166～2.794）和WHR（OR=2.108，95%CI=1.061～4.189）是HUA发生的影响因素；女性VFA（OR=1.775，95%CI=1.154～2.732），WC（OR=2.015，95%CI=1.137～3.570）和WHR（OR=2.489，95%CI=1.400～4.426）均是HUA发生的影响因素。结论内脏脂肪的蓄积会增加HUA的发生风险。加强人群内脏型肥胖的检测对于预防HUA的发生具有重要意义。

Objective To analyze the relationship between visceral obesity and hyperuricemia (HUA), and to provide the basis for the further study of obesity and HUA. Methods A total of 1 824 participants came from Tianjin Heping District Health Education Guidance Center in 2014 were selected in this study. The investigation was performed with physical examination and laboratory test for all subjects. Body fat analyzer was used to measure the visceral fat area (VFA).The Logistic regression analysis was used to evaluate the relationship between visceral obesity and HUA. Results Theprevalence of HUA in men and women increased gradually with VFA increasing (P<0.05). There was a positive correlationbetween VFA, waist circumference (WC), waist-to-hip ratio (WHR) and serum uric acid (SUA) level (P<0.05). According tothe results of Logistic regression analysis, VFA (OR=1.805,95%CI=1.166-2.794) and WHR (OR=2.108,95%CI=1.061-4.189) were the risk factors of HUA in men. And in women, VFA (OR=1.775,95%CI=1.154-2.732), WC (OR=2.015, 95%CI=1.137- 3.570) and WHR (OR=2.489, 95% CI=1.400- 4.426) were the risk factors of HUA. Conclusion The accumulation of visceral fat will increase the risk of HUA. So it is necessary to strengthen the detection of visceral obesity toprevent the development of HUA.