2015年上海市奉贤东部地区手足口病患儿的病原分布与临床特征

Distribution of pathogens and clinical features of children with hand-foot-mouth disease in Fengxian eastern district of Shanghai in 2015

目的:分析2015年上海市奉贤东部地区手足口病患儿的病原分布及其临床特点。方法:收集2015年1-12月上海市奉城医院感染门诊确诊的256例手足口病患儿的相关临床资料,常规采集血标本,采用ELISA法进行病毒早期检测,并分析手足口病患儿的临床特点。结果:256例病毒检测总阳性率为22.27%,其中肠道病毒71型阳性率为12.89%,柯萨奇病毒A组16型阳性率为9.38%。所有病例均为轻症病例,无一例发展为重症病例或死亡。结论:奉贤东部地区2015年手足口病患儿肠道病毒71型、柯萨奇病毒A组16型检出率较低。手足口病防控重点以散居儿童和幼托儿童为主,采取综合有效措施降低手足口病的流行至关重要。

Objective: Distribution of pathogens and clinical features of children with hand-foot-mouth disease in Fengxian easterndistrict of Shanghai in 2015 were analyzed. Methods: Clinial data of 256 cases were collected. Conventional blood samples were collected.Early detection of the virus was implemented by ELISA method. Clinical characteristics of children with HFMD were analyzed. Results:In 256 cases, the total positive ratio of virus was 22.27%, positive ratio of enterovirus type 71 was 12.89%; and positive ratio of Coxsackievirus A group type 16 was 9.38%. All cases were mild cases, with no severe or death cases. Conclusion: Detection ratio of enterovirustype 71 and Coxsackie virus A group type 16 in children with hand-foot-mouth disease in Fengxian eastern district of Shanghai in 2015was lower. Prevention and control of HFMD were focused on scattered children and kindergarten children as the main targets. Takingcomprehensive and effective measures to reduce the prevalence of HFMD is essential.