地佐辛、舒芬太尼在开腹全子宫切除术后静脉自控镇痛效果的对比研究

Comparative study of dezocine and sufentanil in patient controlled intravenous analgesia after open total hysterectomy

目的:探讨地佐辛和舒芬太尼在开腹全子宫切除术后静脉自控镇痛的效果。方法:收治行开腹全子宫切除术患者72例,随机分为地佐辛组和舒芬太尼组,比较两组镇痛效果。结果:地佐辛组患者术后不同时间点的VAS评分与舒芬太尼组比较,差异无统计学意义(P>0.05)。地佐辛组不良反应发生率明显低于舒芬太尼组(P<0.05)。结论:地佐辛与舒芬太尼用于开腹全子宫切除术后静脉自控镇痛均有较好的镇痛效果,但地佐辛的不良反应发生率更低,安全性更高。

Objective:To explore the effect of dezocine and sufentanil in patient controlled intravenous analgesia after open totalhysterectomy.Methods:72 patients with open total hysterectomy were selected.They were randomly divided into the dezocine groupand the sufentanil group.We compared the analgesic effect of two groups.Results:In the dezocine group,compared with thesufentanil group,the differences of VAS scores at different time points after surgery were not statistically significant(P>0.05).Inthe dezocine group,the incidence of adverse reactions was significantly lower than the sufentanil group(P<0.05).Conclusion:They had better analgesic effect of dezocine and sufentanil in patient controlled intravenous analgesia after open total hysterectomy,but the adverse reaction rate of dezocine was lower,and the safety was higher.