埃索美拉唑与奥美拉唑治疗反流性食管炎的效果研究

Study on the effect of esomeprazole and omeprazole in the treatment of reflux esophagitis

目的:探讨奥美拉唑与埃索美拉唑治疗反流性食管炎的效果。方法:收治反流性食管炎患者80例,随机分为埃索美拉唑治疗组(A组)与奥美拉唑治疗组(B组),各40例。结果:两组患者治疗后症状积分值均有降低,A组降低幅度更为显著(P<0.05)。A组反流性食管炎患者总有效率显著高于B组(P<0.05)。结论:埃索美拉唑治疗反流性食管炎效果优于奥美拉唑。

Objective:To evaluate the efficacy of omeprazole and esomeprazole in the treatment of reflux esophagitis.Methods:80patients with reflux esophagitis were selected.They were randomly divided into the esomeprazole treatment group(A group)andthe omeprazole treatment group(B group)with40cases in each.Results:After the treatment,the symptom scores of the two groupswere decreased,and the A group was significantly lower(P<0.05).The total effective rate of reflux esophagitis in the group A wassignificantly higher than that of the B group(P<0.05).Conclusion:Esomeprazole in the treatment of reflux esophagitis is betterthan omeprazole.