磁共振弥散张量成像对弥漫性轴索损伤的临床评估价值

Clinical value of magnetic resonance diffusion tensor imaging in diffuse axonal injury

目的:探讨磁共振弥散张量成像(DTI)对弥漫性轴索损伤(DAI)的临床评价价值。方法:收治DAI患者41例为观察组,选择健康体检者41例为对照组,行DTI检查,并测量血清MBP含量,分析血清MBP水平与FA值的相关性。结果:观察组颅脑各区域FA值均明显低于对照组,血清MBP水平明显高于对照组(P<0.05)。DAI患者FA值与血清MBP水平呈负相关(r=-0.817,P=0.001)。结论:DTI可无创反映DAI患者的颅脑损伤情况,对DAI的诊断与预后评估具有较高价值。

Objective:To explore the clinical value of magnetic resonance diffusion tensor imaging(DTI)in diffuse axonalinjury(DAI).Methods:41patients with DAI were selected as the observation group,41healthy persons were selected as the controlgroup.They were given DTI examination and determination of MBP content in serum,and we analyzed the correlation betweenserum MBP levels and FA values.Results:In the observation group,the FA value of each area of brain was significantly lower thanthat of the control group,and the level of serum MBP was significantly higher than that of the control group(P<0.05).In DAIpatients,FA value was negatively correlated with serum MBP levels(r=-0.817,P=0.001).Conclusion:DTI can reflect the braindamage of DAI patients without hurt,and had high value for diagnosis and prognosis assessment of DAI.