摘要
石墨烯是一种由碳原子以sp2杂化轨道组成的六角型平面多环芳香烃原子晶体。基于石墨烯的纳米材料具有卓越的理化性质,近年来在医疗应用领域的研究成为热点,可用在药物载体、基因传递、生物检测、肿瘤治疗、抗菌和组织工程等方面。该文综述了石墨烯材料的性能、制备方法和众多衍生物的特性,介绍了石墨烯类材料在组织工程方面的研究进展,包括在创伤愈合、干细胞工程、肌肉骨骼工程方向的应用,展望了石墨烯在组织工程领域未来的发展。
Graphene is one of the crystalline forms of carbon,which is composed of a single monolayer of sp2hybridized orbitals tightly packed to atwo-dimensional honeycomb lattice.Because of its remarkable physiochemical properties,graphene based nanomaterials have become a hot researchtopic in the field of biological applications,which are available in drug delivery,gene delivery,biological detection,tumor treatment,antibacterial,tissueengineering,etc.This paper reviews the material properties,preparation methods and many derivatives of graphene,and introduces the research progressof graphene based materials in tissue engineering,including the application in wound healing,stem cell engineering,skeletal muscle engineering.Thefuture development of graphene in the field of tissue engineering is prospected.
作者
曹忆梦
吴氢凯
CAO Yi-meng;WU Qing-kai(Graduate Department, Medical college of Soochow University, Suzhou 215123, China;Department of Obstetrics and Gynecology, Shanghai Sixth People’s Hospital,Shanghai Jiao Tong University, Shanghai 200233, China)
出处
《上海交通大学学报(医学版)》
CAS
CSCD
北大核心
2017年第1期110-113,共4页
Journal of Shanghai Jiao tong University:Medical Science
基金
国家自然科学基金(81550008)~~