益生菌加康复新液治疗活动期轻中度溃疡性结肠炎的效果及安全性观察

Effect and safety observation of probiotics combined with Kangfuxin liquid in the treatment of mild and moderate active ulcerative colitis

目的:探讨益生菌加康复新液治疗活动期轻中度溃疡性结肠炎的临床效果以及安全性。方法:收治活动期轻中度溃疡性结肠炎患者48例,随机分为两组。对照组给予益生菌治疗,观察组给予益生菌加康复新液治疗,比较两组临床疗效以及安全性。结果:观察组临床总有效率明显优于对照组,差异具有统计学意义(P<0.05)。观察组结肠镜下病变活动性评分明显低于对照组,差异具有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论:益生菌加康复新液治疗活动期轻中度溃疡性结肠炎的临床疗效显著。

Objective:To investigate the clinical effect and safety of probiotics combined with Kangfuxin liquid in the treatment of mild and moderate active ulcerative colitis.Methods:48 cases of patients with mild and moderate active ulcerative colitis were divided into two groups randomly.The control group was treated with probiotics.The observation group was treated with probiotics combined with Kangfuxin liquid.The clinical curative effect and safety of the two groups were compared.Results:The total effectiverate of the observation group was significantly better than that of the control group,and the difference was statistically significant (P<0.05).The colon endoscopic lesion activity score of the observation group was significantly lower than that of the control group,and the difference was statistically significant (P<0.05).The incidence of adverse reactions in the observation group was lower than that of the control group,and the difference was statistically significant (P<0.05).Conclusion:Probiotics combined with Kangfuxin liquid in the treatment of mild and moderate active ulcerative colitis had more significant clinical effect.