多种血清肿瘤标志物(CY211、NSE、CEA、CA125、CA199、SCC)对不同病理类型和临床分期肺癌的诊断价值

Diagnostic value of multiple serum tumor markers(CY211,NSE,CEA,CA125,CA199,SCC) in different pathological types and clinical stages of lung cancer

目的:分析多种血清肿瘤标志物(CY211、NSE、CEA、CA125、CA199、SCC)对不同病理类型和临床分期肺癌的诊断价值。方法:收治肺癌患者80例,采取化学发光法测定患者血清中CY211、NSE、CEA、CA125、CA199、SCC的水平。结果:鳞癌患者SCC阳性率最高,阳性率52.6%;腺癌患者CEA阳性率最高,阳性率45.2%。鳞癌患者分期中Ⅱ期、Ⅲ期的SCC阳性率明显高于Ⅰ期(P<0.05)。结论:联合检查能有效提高肺癌诊断率的准确性,临床检查中,医生可根据患者的病理类型选择不同的血清标志物进行联合检查。

Objective:To analyze the diagnostic value of multiple serum tumor markers(CY211,NSE,CEA,CA125,CA199,SCC) in different pathological types and clinical stages of lung cancer.Methods:80 patients with lung cancer were selected.The levels of CY211,NSE,CEA,CA125,CA199,SCC in the serum of patients were determined by chemiluminescence method.Results:The highest positive rate of squamous cell carcinoma was SCC,and the positive rate was 52.6% .The highest positive rate of adenocarcinoma was CEA,and the positive rate was 45.2% .In the stages of patients with squamous cell carcinoma,the positive rates of SCC in Ⅱstage、Ⅲstage were significantly higher than that of Ⅰstage(P<0.05).Conclusion:Combined examination can effectively improve the accuracy of diagnosis rate of lung cancer.In the clinical examination,the doctor may choose different serumm arkers according to the patient's pathological type to carry out a combined examination.