血清前白蛋白联合高尔基体蛋白73在肝病检测及治疗过程中的应用

Application of serum prealbumin combined with golgi protein 73 in the detection and treatment of liver disease

目的:探讨血清前白蛋白(PA)联合高尔基体蛋白73(GP73)在肝病检测及治疗中的价值。方法:收治肝病患者149例为试验组,选择健康体检者40例为对照组,进行血清前白蛋白及GP73蛋白检测,比较两组检测结果。结果:试验组血清PA含量显著低于对照组(P<0.01),GP73含量显著高于对照组(P<0.05)。急性肝炎组79.5%患者PA值下降,白蛋白9.7%患者下降,差异有统计学意义(P<0.01)。结论:PA联合GP73蛋白检测较ALB能更灵敏地早期反映肝脏细胞受损程度。

Objective:To explore the application effect of serum prealbumin combined with golgi protein 73 in the detection and treatment of liver disease.Methods:149 patients with liver disease were selected as the experimental group.40 healthy subjects were selected as the control group.They were given serum prealbumin and GP73 protein test.We compared the results of thedetection of two groups.Results:In the experimental group,the serum PA content was significantly lower than the control group(P<0.01),and GP73 content was significantly higher than the control group(P<0.05).In the acute hepatitis group,the PA value of79.5% patients was decreased,and albumin of 9.7% patients was decreased;the difference was statistically significant(P<0.01).Conclusion:Compared with ALB,PA combined with GP73 protein detection can more sensitively reflect the degree of liver cell damage in the early.