牙髓根尖周病的治疗新方法:再生牙髓病学之路

New treatment modality for pulpititis and apical periodontitis: pathway of regenerative endodontics

为促进牙髓牙本质复合体的再生,学者们将组织工程学技术应用于牙髓治疗中,并提出了再生牙髓病学的概念。作为口腔医学的新兴学科,再生牙髓病学运用牙源性干细胞、生物支架以及生长因子等因素促进牙根继续发育和牙髓组织再生。临床上,牙髓再生技术已应用于治疗年轻恒牙牙髓坏死及根尖周炎,越来越多的病例报道或研究结果显示牙髓再生的可能性,牙髓再生治疗将成为口腔医生治疗牙髓病的新选择。本文就再生牙髓病学的现状和发展进行总结分析。

Tissue engineering has been applied to induce pulp?dentin complex regeneration,and proposed the con?cept of regenerative endodontics.As a new subject in stomatology,regenerative endodontics promotes root development and pulp regeneration with the combination of dental stem cells,biomaterial scaffolds and growth factors.Clinically,pulp regenerative technique has been used to treat necrosis and periapical periodontitis of immature permanent teeth.Numerous case reports and studies have proved the possibility of pulp regeneration,and regenerative endodontics willbecome a potential new treatment alternative of dental pulp diseases for dental clinician.In the present paper,we willsummarize and analyze the current process and prospective of regenerative endodontics.