G试验在COPD合并侵袭性肺部真菌感染诊断中的临床价值

G test in COPD patients with invasive pulmonary fungal infection diagnosis Clinical Value

目的：探讨1,3-β-D葡聚糖检测（G试验）在慢性阻塞性肺疾病（COPD）合并侵袭性肺部真菌感染诊断中的应用价值。方法：回顾性调查2015年6月至2016年6月洛阳市中心医院158例确诊为COPD合并真菌感染患者，此研究对象同时做G试验检测、痰液真菌培养和影像学检查，将三者结果进行比较。结果：158例患者中108例患者真菌培养阳性，其中白色念珠菌54例，热带念珠菌23例，克柔念珠菌20例，光滑念珠菌9例，近平滑假丝酵母菌2例。根据G试验含量将该实验分为两组，再分别对组内的患者进行真菌培养结果和影像学检查结果进行研究。结论：G试验较真菌培养和影像学检查特异性高,可作为COPD合并侵袭性肺部真菌感染的辅助诊断。

Objective :Objective: Discussion 1,3-β-D-glucan detection (G test) value in the diagnosis of chronic obstructive pulmonary disease (COPD) combined invasive pulmonary fungal infections. Methods: A retrospective survey from June 2015 to June 2016 Luoyang Central Hospital 158 cases diagnosed as fungal infection in patients with COPD, is study while doing G test for detection of sputum fungal culture and imaging studies, the results were compared with the three methods.Results: ere are 108 patients with fungal culture positive patients in the 158 patients. 54 cases Candida albicans, 23 cases Candida tropicalis , 20 cases krusei, 9 cases glabrata, 2 cases nearly smooth Candida.Conclusions: G test comparing fungal culture and imaging with high speci city, G test can be combined as COPD diagnosis with invasive pulmonary fungal infections.