药师干预对出院短暂性脑缺血发作患者认知程度和用药依从性的影响研究

Research of influence by pharmacist intervention on cognition degree and medication compliance in discharged transient ischemic attack patients

目的研究药师干预对出院短暂性脑缺血发作患者对用药知识的认知程度和用药依从性的影响。方法 150例短暂性脑缺血发作的患者随机分为对照组和干预组,各75例。对照组在出院时护士将药物发给患者并进行简单用药指导,药师不予干预。干预组在出院时将药物发放给患者,并由药师对患者或者长期看护人进行用药交代,制定指导单,讲解后交与患者或者长期看护人。观察两组患者用药依从情况及对用药知识认知程度等的差异。结果经统计,对照组完全依从14例、部分依从43例、不依从18例,干预组完全依从31例、部分依从44例、不依从0例,干预组依从性优于对照组,差异具有统计学意义(P<0.05)。出院3周后干预组的降压药问题回答情况、调脂药问题回答情况、药物各剂型用法问题回答情况均优于对照组,差异具有统计学意义(P<0.05)。结论药师对短暂性脑缺血发作患者出院带药进行指导交待,能有效地提高患者的认知程度和用药依从性,保障用药的有效安全,在临床上值得推广。

Objective To research influence by pharmacist intervention on cognition degree and medication compliance in discharged transient ischemic attack patients. Methods A total of 150 patients with transient ischemic attack were randomly divided into control group and intervention group, with 75 cases in each group. The control group received simple medication guidance without pharmacist intervention during medicine distribution. The intervention group received medication explanation and guidance list by pharmacist for patients or long-term keeper. Observation was made on differences of medication compliance status and cognition degree of medication knowledge between the two groups. Results Summary showed 14 complete compliance cases,43 partial compliance cases and 18 noncompliance cases in the control group, while there were 31 completecompliance cases, 44 partial compliance cases and 0 noncompliance case in the intervention group. Theintervention group had better compliance than the control group, and their difference had statistical significance(P<0.05). In 3 weeks after discharge, the intervention group had all better answers for hypotensive drugs questions,lipid regulation drugs, medication dosage and usage than the control group, and the difference had statistical significance (P<0.05). Conclusion Guidance and explanation by pharmacist on discharge medication in transient ischemic attack patients can effectively improve cognition degree and medication compliance in patients and guarantee effectiveness and safety in medication. This method is worth clinical promotion.