ST段抬高型心肌梗死患者经PCI后应用替格瑞洛与氯吡格雷的临床疗效及安全性比较

Comparison of clinical effect and safety of ticagrelor and clopidogrel applied in patients with ST segment elevation myocardial infarction after PCI

目的:比较ST段抬高型心肌梗死患者经PCI后应用替格瑞洛与氯吡格雷的临床疗效及安全性。方法:收治行PCI治疗的ST段抬高型心肌梗死患者80例,分为两组。对照组给予氯吡格雷治疗,观察组给予替格瑞洛治疗,比较两组心血管事件发生率、左心功能。结果:观察组心血管事件发生率5.00%,低于对照组(P<0.05)。观察组LVEDV、LVESV、LVDs、LVEF均优于对照组(P<0.05)。结论:替格瑞洛治疗行PCI治疗的ST段抬高型心肌梗死患者可明显改善左心功能。

Objective:To compare the clinical effect and safety of ticagrelor and clopidogrel applied in patients with ST segmentelevation myocardial infarction after PCI.Methods:80cases of patients with ST segment elevation myocardial infarction treatedwith PCI were divided into two groups.The control group was treated with clopidogrel.The observation group was treated withticagrelor.The incidence of cardiovascular events and left ventricular function between groups were compared.Results:Theincidence of cardiovascular events in the observation group was5.00%,which was lower than that in the control group(P<0.05).The LVEDV,LVESV,LVDs and LVEF in the observation group were better than those in the control group(P<0.05).Conclusion:Ticagrelor in the treatment of patients with ST segment elevation myocardial infarction after PCI could improve the left ventricularfunction.