高渗盐水治疗重型颅脑创伤合并休克患者的临床应用价值

Clinical value of hypertonic saline in the treatment of severe traumatic brain injury complicated with shock

目的:探讨高渗盐水治疗重型颅脑创伤合并休克患者的应用价值。方法:收治重型颅脑损伤合并休克患者76例,随机分成试验组和对照组各38例。对照组给予甘露醇治疗,试验组给予高渗盐水治疗。结果:治疗后,试验组患者MAP、CPP、APACHE Ⅱ、GCS评分均明显高于对照组(P<0.05)。结论:高渗盐水治疗重型颅脑创伤合并休克患者的临床应用价值显著,能够增加患者MAP、CPP以及GCS评分,同时还能降低患者APACHE Ⅱ评分。

Objective:To investigate the application value of hypertonic saline in the treatment of severe traumatic brain injurycomplicated with shock.Methods:76patients with severe craniocerebral injury combined with shock were selected.They wererandomly divided into the experimental group and the control group with38cases in each.The control group was treated withmannitol,while the experimental group was treated with hypertonic saline.Results:After the treatment,the MAP,CPP,APACHE,andGCS scores of the experimental group were significantly higher than those of the control group(P<0.05).Conclusion:The clinicalvalue of hypertonic saline in the treatment of patients with severe craniocerebral trauma combined with shock is significant,whichcan increase the MAP,CPP and GCS score of patients,and also can reduce the APACHE score of patients.