恩替卡韦治疗失代偿期乙肝肝硬化临床疗效观察

Clinical effect of entecavir in the treatment of decompensated hepatitis B cirrhosis

目的:探讨恩替卡韦治疗失代偿期乙肝肝硬化患者的临床效果。方法:收治失代偿期乙肝肝硬化患者60例,随机分成对照组和观察组,对照组采用阿德福韦酯治疗,观察组采用恩替卡韦治疗,比较两组治疗效果。结果:观察组治疗总有效率、并发症发生率及肝功能恢复指标均明显优于对照组(P<0.05)。结论:恩替卡韦治疗失代偿期乙肝肝硬化患者的临床效果显著。

Objective:To explore the clinical effect of entecavir in the treatment of decompensated hepatitis B cirrhosis.Methods:60patients with decompensated hepatitis B cirrhosis were selected.They were randomly divided into the control group and the observation group.The control group was treated with adefovir dipivoxil.The observation group were treated with entecavir.We compared the therapeutic effect of two groups.Results:In the observation group,the total effective rate of treatment,the incidence of complications and the recovery of liver function were significantly better than those of the control group(P<0.05).Conclusion:The clinical effect of entecavir in the treatment of decompensated hepatitis B cirrhosis was significant.