细菌性肝脓肿患者手术前后血清白细胞介素10的表达及其临床意义

Expression of serum interleukin 10 in patients with bacterial liver abscess before and after operation and its clinical significance

目的探讨细菌性肝脓肿患者手术前后血清白细胞介素10(IL-10)的表达及其临床意义。方法选择2014年1月~2016年2月诊治的细菌性肝脓肿患者72例,根据治疗方法的不同分为观察组与对照组,各36例,对照组给予穿刺引流治疗,观察组给予手术治疗,记录两组预后与IL-10表达变化。结果治疗后,经过判断,观察组的总有效率为97.2%,高于对照组为86.1%(P<0.05)。观察组与对照组治疗后的血清IL-10表达量分别为(56.01±16.24)pg/m L和(112.35±19.34)pg/m L,都明显低于治疗前的(178.23±25.52)pg/m L和(180.34±27.76)pg/m L(P<0.05),治疗后观察组也明显低于对照组(P<0.05)。结论相对于穿刺治疗,细菌性肝脓肿患者采用手术治疗具有更好的疗效,能使血清IL-10的表达降低,有很好的应用价值。

Objective To investigate the expression and clinical significance of serum interleukin10(IL-10)in patients with bacterial liver abscess before and after operation.Methods From January2014to February2016,72cases of diagnosis and treatment of bacterial liver abscess patients were selected and divided into observation group and control group with36patients in each group accorded to the different treatment methods,the control group was given puncture treatment,the observation group was given surgical treatment,the expression of IL-10and the prognosis of two groups were recorded.Results After treatment,the effective rate of observation group was97.2%,the control group was86.1%,the observation group was significantly higher than that of the control group(P<0.05).The the serum IL-10expression level in the observation group and the control group after treatment were(56.01±16.24)pg/mL and(112.35±19.34)pg/mLrespectively,were significantly lower than those before treatment of(178.23±25.52)pg/mL and(180.34±27.76)pg/mL(P<0.05),the observation group after treatment was significantly lower than the control group(P<0.05).Conclusion Compared with the puncture treatment,bacterial liver abscess patients with surgical treatment has a better effect,it can promote the expression of serum IL-10decreased,there is a good application value.