自制气道温湿化装置在经人工气道自主呼吸患者中的应用

Application of Self-Made Airway Humidifying Device on Artificial Airway Self-Breathing Patients

目的观察自制气道温湿化装置对经人工气道自主呼吸患者临床症候、痰液粘稠度、白细胞(White Blood Cell,WBC)计数及降钙素原(Procalcitonin,PCT)、动脉血氧分压(PO2)和二氧化碳分压(PCO2)的影响。方法将40例建立人工气道患者随机分成治疗组和对照组,对照组使用斯莱达EM06-003L型氧气雾化装置,治疗组使用自制气道温湿化装置,两组均使用灭菌注射用水进行气道湿化,共治疗2周,分别记录两组患者临床症候、痰液粘稠度、WBC计数及PCT、PO2和PCO2。结果两组在治疗前一般资料、痰液粘稠度、WBC计数及PCT、PO2、PCO2等方面无明显差异(P>0.05),经过治疗,两组临床症候、痰液粘稠度、WBC计数及PCT均有改善,治疗组均明显优于对照组(P<0.05),对照组PO2有所下降,PCO2有所升高,治疗组PO2有所升高,PCO2有所下降,效果明显优于对照组(P<0.05)。结论自制气道温湿化装置对经人工气道自主呼吸患者进行气道温湿化,能有效改善临床症候及痰液粘稠度,改善WBC计数、PCT,并能很好的改善氧合及避免发生CO2潴留。

Objective To observe the effect of self-made airway humidifying device on artificial airway selfbreathingpatients in terms of their spontaneous breathing symptoms, sputum viscosity, White Blood Cell count (WBC) and Procalcitonin (PCT), Arterial Oxygen Partial Pressure (PO2) and Carbon Dioxide Partial Pressure (PCO2). Methods 40 patients with artificial airway were randomly divided into two groups: the treatment group and the control group. The control group used EM06003Lstarlight oxygen atomization device, while the treatment group used selfmadeairway humidifying device. Sterile water was used for injection for airway humidification on both two groups. A total of 2 weeks of treatment were recorded about their clinical symptoms, sputum viscosity, WBC, PO2 and PCO2 count and PCT. Results Before treatment, there was no significant difference (P>0.05) between the two groups in their general information,sputum viscosity, WBC count, PCT, PO2, PCO2, etc; after treatment, the clinical symptoms, sputum viscosity,WBC count and PCT were improved in both groups, and the treatment group was significantly better than the control group (P<0.05). The PO2 of the control group was decreased, and the PCO2 increased; the PO2 of the treatment group was increased and the PCO2 decreased, and the effect was better than that of the control group (P<0.05). Conclusion The self-made airway humidifying device for the artificial airway selfbreathingpatients can effectively improve the clinical symptoms, sputum viscosity, WBC count and PCT, and can also improve the oxygenation and avoid the occurrence of CO2 retention.