洛索洛芬钠超前镇痛对子宫动脉栓塞术后疼痛的临床疗效分析

An analysis of clinical effect of loxoprofen sodium on alleviating the pain after uterine artery embolization

目的:探讨洛索洛芬钠对子宫动脉栓塞术(UAE)疼痛超前镇痛中的临床应用效果及可行性评价。方法:便利抽样法选取2016年1月——8月在包头医学院第一附属医院介入治疗科实施UAE治疗子宫肌瘤的患者24例,分为观察组12例和对照组12例。观察组于术前3 d~术后3 d口服洛索洛芬钠60mg/次,3次/d;对照组仅于术后3 d口服洛索洛芬钠60 mg/次,3次/d。比较两组术后不同时间(0、4、8、16、24、48h)的视觉模拟评分(VAS)以评价疼痛程度,采用布氏舒适评分(BCS)评价舒适程度。结果:观察组患者术后0、4、8、16、24、48 h的VAS评分均明显低于对照组,差异均有统计学意义(P<0.01);而观察组患者术后0、4、8、16、24、48 h的BCS评分明显高于对照组,差异均有统计学意义(P<0.05)。结论:洛索洛芬钠超前镇痛能安全有效地用于UAE,可降低术后疼痛的程度,提高患者的舒适程度和满意度。

Objective:To evaluate the clinical effect and feasibility of loxoprofen sodium in efficientlyalleviating the pain after uterine artery embolization(UAE)pain.Methods:Twenty-four patients with uterinefibroids treated with UAE in our hospital between January and August in2016were selected for this study.Theywere randomly divided into observation group(n=12)and control group(n=12).The observation group weretreated with loxoprofen sodium60mg/time and3times/day while control group received an oral administration ofloxoprofen sodium60mg/?.The visual analogue scale(VAS)of the two groups at different time(0,4,8,16,24,48h)was compared to evaluate the degree of the pain.The comfort degree was evaluated by Brinell comfort score(BCS).Results:The VAS scores of the observation group were significantly lower than those of the control group at0,4,8,16,24and48h after operation(P<0.01).The BCS scores of0,4,8,16,24,48h of the observation group weresignificantly higher than those of the control group(P<0.05).Conclusions:The loxoprofen sodium can greatlyreduce the degree of postoperative pain of UAE and improve the comfort and satisfaction of patients,thus,it is worthof clinical application.