小儿咳嗽变异性哮喘与肺炎支原体感染相关性探讨

Study on the relationship between cough variant asthma and Mycoplasma pneumoniae infection in children

目的分析小儿咳嗽变异性哮喘与肺炎支原体感染相关性。方法选择80例咳嗽变异性哮喘患儿为实验组,90例肺炎支原体感染小儿为对照组,检测两组小儿血清肺炎支原体Ig M抗体、外周血嗜酸性颗粒细胞计数和血清总Ig E水平,对比两组小儿肺炎支原体Ig M抗体阳性率以及支原体Ig M抗体阳性小儿外周血嗜酸性颗粒细胞计数和血清总Ig E水平。结果实验组肺炎支原体Ig M抗体的阳性率为(37.5%);对照组90例肺炎支原体Ig M抗体的阳性率为(12.2%),实验组显著高于对照组,差异有统计学意义(P<0.05);实验组肺炎支原体Ig M抗体阳性小儿的血清总Ig E水平(175.58±45.62)和嗜血酸性颗粒细胞计数为(7.82±5.13)明显优于对照组的(90.54±50.36)和(2.36±2.14),差异具有统计学意义(P<0.05)。结论肺炎支原体感染是小儿咳嗽变异性哮喘引发的危险原因,小儿咳嗽变异性哮喘容易引发肺炎支原体感染,两者之间关系比较密切。

Objective To analyze the relationship between children with cough variant asthma and mycoplasma pneumoniaeinfection.Methods80children with cough variant asthma were selected as experimental group and90cases with Mycoplasma pneumoniae infection as control group.IgM antibody,eosinophil granulocyte count and total serum IgE in serum of two groups were detected.Group of children with mycoplasma pneumonia mycoplasma IgM antibody positive rate and mycoplasma IgM antibody positive children peripheral blood eosinophil granulocyte count and serumtotal IgElevels.Results The positive rate of mycoplasma IgM antibody in the experimental group was(37.5%).The positive rate of IgM antibodyin the control group was(12.2%),which was significantly higher than that in the control group(P<0.05);The serum total IgE level and bloodglucose granulocyte count in the experimental group were significantly higher than those in the control group(90.54±50.36)and(2.36±2.14),thedifference was significant With statistical significance(P<0.05).Conclusion Mycoplasma pneumoniae infection is a risk factor for cough variantasthma in children.Mycoplasma pneumoniae infection may be caused by cough variant asthma in children,and the relationship between them isclose.