西替利嗪加自血穴位注射治疗慢性荨麻疹疗效观察

Observation on curative effect of cetirizine and autologous blood acupoint-injection in the treatment of chronic urticaria

目的探讨慢性荨麻疹采用西替利嗪联合自血穴位注射治疗的临床效果。方法 80例慢性荨麻疹患者,随机分为对照组和观察组,每组40例。对照组患者实施西药西替利嗪糖浆治疗,观察组患者实施西替利嗪糖浆联合自血穴位注射治疗,观察两组患者治疗后的临床疗效情况。结果两组治疗后,患者的瘙痒、风团数量及风团大小评分均有所改善,但观察组患者评分的下降幅度显著优于对照组,差异有统计学意义(P<0.05)。观察组治疗后复发率为2.5%显著低于对照组治疗后的22.5%,差异有统计学意义(P<0.05);观察组的总有效率92.5%略高于对照组的87.5%,但差异无统计学意义(P>0.05)。结论西替利嗪联合自血穴位注射治疗慢性荨麻疹,有效的改善了患者的临床症状,提高了患者的生活质量,降低了荨麻疹的复发率,疗效确切,安全性高,值得临床推广应用。

Objective To explore the clinical effect of chronic urticaria treated with cetirizine and autologous blood acupoint-injection. Methods A total of 80 chronic urticaria patients were randomly divided into control group and observation group, with 40 cases in each group. The control group received western medicine cetirizine syrup for treatment, and the observation group received cetirizine syrup combined with autologous blood acupoint-injection fo treatment. Clinical curative effect was compared in two groups. Results After treatment, both groups had improved pruritus, wheal quantity and wheal size score, but the observation group had better decline range than the control group, and the difference had statistical significance (P<0.05). The observation group had obviously lower recurrence rate as 2.5% after treatment than 22.5% in the control group after treatment, and the difference had statistical significance (P<0.05). The observation group had a little higher total effective rate as 92.5% than 87.5% in the control group, but the difference had no statistical significance (P>0.05). Conclusion Combination of cetirizine and autologous blood acupoint-injection in treating chronic urticaria, can effectively improve the clinical symptoms of patients, increase their quality of life, decrease urticaria recurrence rate with affirmative curative effect and high security, and it is worth clinical promotion and application.