绝经后女性身体成分与骨量的相关性分析

Correlation analysis between body composition and bone mass in postmenopausal women

目的探讨绝经后女性身体成分与骨量的相关性及其应用价值。方法回顾性分析2015年6月至2016年5月在揭阳市人民医院体检科接受身体成分分析的80例绝经后女性的临床资料。所有患者均签署知情同意书,符合医学伦理学规定。根据检测的骨量值将受试者分为正常骨量组和低骨量组。其中正常骨量组17例,年龄(60±6)岁;低骨量组63例,年龄(61±5)岁。比较两组患者年龄、身高、体质量、脂肪含量、肌肉质量、推定骨量、骨比重、雌激素水平、体脂率、肌肉率等指标。两组资料的比较采用t检验,骨比重与体脂率和肌肉率的相关性分析采用Pearson相关分析法。结果低骨量组受试者的体质量、脂肪含量、体脂率分别为(62±7)kg、(22.8±3.3)kg和(37±5)%,明显高于正常骨量组的(57±7)kg、(19.1±2.3)kg和(33±4)%(t=2.222、4.228、2.685,P<0.05);低骨量组受试者的推定骨量、骨比重、肌肉率和雌二醇含量分别为(1.94±0.28)kg、(3.2±0.5)%、(60±5)%和(51±7)pg/ml,明显低于正常骨量组的(2.26±0.27)kg、(3.9±0.3)%、(63±4)%和(69±8)pg/ml(t=4.212、6.584、2.092、9.223,P<0.05)。绝经后女性的骨比重和体脂率呈负的直线相关关系(Y=–12.84X+0.84,r=–0.742,P<0.001),骨比重和肌肉率呈正的直线相关关系(Y=11.96X+0.16,r=0.696,P<0.001)。结论绝经后女性的骨量与体脂和肌肉变化有关,故分析体脂率和肌肉率可能有助于评估和预测绝经后女性发生骨质疏松症的风险。

Objective To investigate the correlation between body composition and bone mass inpostmenopausal women and its application value.Methods Clinical data of80postmenopausal womenaccepting body composition analysis in the Medical Examination Center of the People’s Hospital of Jieyangfrom June2015to May2016were retrospectively studied.The informed consents of all women wereobtained and the local ethical committee approval had been received.According to the bone mass value,thesewomen were divided into the normal bone mass group and the low bone mass group.Seventeen women wereincluded into the normal bone mass group with an average age of(60±6)years old,and the other63womenwere included into the low bone mass group with an average age of(61±5)years old.The indexes of age,height,body weight,fat content,muscle quality,presumptive bone mass,bone proportion,estrogen,body fatand muscle rate were compared between the two groups.The data of the two groups were compared using ttest,and the correlation analyses between bone proportion and body fat and muscle rate were conducted usingPearson correlation analysis.Results The body weight,fat content and body fat rate of the women in thelow bone mass group were(62±7)kg,(22.8±3.3)kg and(37±5)%respectively,which were significantlyhigher than(57±7)kg,(19.1±2.3)kg and(33±4)%of those women in the normal bone mass group(t=2.222,4.228,2.685,P<0.05);the presumptive bone mass,bone proportion,muscle rate and estrogen levelof the women in the low bone mass group were(1.94±0.28)kg,(3.2±0.5)%,(60±5)%and(51±7)pg/mlrespectively,which were significantly lower than(2.26±0.27)kg,(3.9±0.3)%,(63±4)%and(69±8)pg/mlof those women in the normal bone mass group(t=4.212,6.584,2.092,9.223,P<0.05).Bone proportion wasnegatively correlated with body fat rate(Y=–12.84X+0.84,r=–0.742,P<0.001),but positively correlatedwith muscle rate(Y=11.96X+0.16,r=0.696,P<0.001).Conclusion Bone mass is related with the changeof body fat and muscle in postmenopausal women,so analyzing body fat and muscle rate may contribute toevaluating and forecasting the risk of osteoporosis in postmenopausal women.