脑梗死患者NIHSS评分与预后的相关性研究

Correlation between NIHSS score and prognosis in patients with cerebral infarction

目的:探讨脑梗死患者的NIHSS评分与预后的关系。方法:收治脑梗死患者328例,根据NIHSS评分分为低值组、中值组和高值组,比较3组临床资料、实验室检查和死亡率。根据临床转归再将患者分为存活组和死亡组,比较组间NIHSS评分差异性。结果:患者死亡率随NIHSS评分的增高而增高(P<0.001)。死亡组NIHSS评分显著高于存活组(P<0.001)。以NIHSS评分预判死亡时,约登指数最大为0.603,此时,其曲线下面积0.879,最佳截断值9.5,敏感度0.875,特异度0.728。结论:NIHSS评分与脑梗死患者预后密切相关,对预后的评估有重要的参考价值。

Objective:To investigate the relationship between NIHSS score and prognosis in patients with cerebral infarction. Methods:328 patients with cerebral infarction were selected,according to the NIHSS score.They were divided into the low value group,the middle value group and the high value group.We compared the clinical data,laboratory tests and mortality rates of the three groups.According to the clinical outcome,patients were divided into the survival group and the death group,and we compared the difference of NIHSS scores between groups.Results:The mortality rate of patients was increased with the increase of NIHSS score(P<0.001).The NIHSS score of the death group was significantly higher than that of the survival group(P<0.001).The NIHSS score was used to predict death,the maximum Youden index was 0.603;the area under the curve was 0.879;the optimal cut-off value was 9.5;the sensitivity was 0.875;the specificity was 0.728.Conclusion:NIHSS score was closely related to the prognosis of patients with cerebral infarction,and it had important reference value for the evaluation of prognosis.